Functionalization

Hummingbird Scientific and Dune Sciences


Surface functionalization of membrane window chips can greatly enhance liquid- and gas-cell, as well as other in-situ TEM experiments. Recognizing this, Hummingbird Scientific and Dune Sciences have entered into an exclusive partnership, combining Hummingbird’s specialized liquid and gas cell and other in-situ microscopy holders and chips with Dune Sciences’ full range of surface functionalization products.

Dune Sciences Smart Grids™ Technology

dune-smart-gridFunctionalized substrates enhance imaging and analysis in in-situ microscopy.  Dune Sciences offers functionalized for nearly any material or assay.

Benefits:

  • Simplifies sample preparation and improves dispersion/uniformity of coverage.
  • Eliminates artifacts such as agglomeration from sample preparation
  • Localizes samples on one membrane to improve image focus and resolution
  • Isolates/tethers biomolecules and nanomaterials through bifunctional linkers or immunocapture

 Applications:

dune-diagram

  • Environmental transformations of nanomaterials
  • Immobilization of biological structures on substrates
  • Dynamic imaging of self-assembly processes
  • On-grid assays

 Surface chemistry options include:

    • Silanization/chemical derivatization
    • Positive or negative surface charges
    • Custom hydrophobic/hydrophilic coatings
    • Self-assembled monolayers
    • Patterned surface chemistry
    • Immunospecific chemistries for purifying/isolating target analytes
STEM Image of 1.5 nm AuMES in water, immobilized on a Hummingbird fluid cell with a positively functionalized surface. (Image taken with a Hummingbird Scientific holder, courtesy of John Miller, Dune Sciences Inc.)
STEM Image of 1.5 nm Au MES in water, immobilized on a Hummingbird fluid cell with a positively-functionalized surface. (Image taken with a Hummingbird Scientific holder, courtesy of John Miller, Dune Sciences Inc.)

Contact Hummingbird Scientific directly for more information.

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