Biomedical & Biological Imaging

Sequence of in-situ TEM images with Hummingbird Scientific liquid holder showing nucleation of CaCO3 on Au. Image at t=0 shows initial gold electrode. By 38 s, CaCOs nanoparticles have nucleated. By 120 s, these nuclei have coalesced and transformed into faceted CaCO3 with the typical calcite morphology. At later times, continued growth and coarsening results in a few dominant crystallites. Experiments conducted with stagnant liquid.
Reference: Nielsen MH, Lee JRI, Hu Q, Yong-Jin Han T, De Yoreo JJ. Structural evolution, formation pathways and energetic controls during template-directed nucleation of CaCO3. Faraday Discuss. 2012;159:105-121. Abstract
Copyright © 2012, the Royal Society of Chemistry.