Functionalization

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Hummingbird Scientific and Dune Sciences


Surface functionalization of membrane window chips can greatly enhance liquid- and gas-cell TEM experiments. Recognizing this, Hummingbird Scientific and Dune Sciences have entered into an exclusive partnership, combining Hummingbird’s specialized liquid and gas cell TEM holders and chips with Dune Sciences’ full range of surface functionalization products.

Dune Sciences Smart Grids™ Technology

dune-smart-gridFunctionalized substrates enhance imaging and analysis in liquid and gas-cell TEM.  Dune Sciences offers functionalized for nearly any material or assay.

Benefits:

  • Simplifies sample preparation and improves dispersion/uniformity of coverage.
  • Eliminates artifacts such as agglomeration from sample preparation
  • Localizes samples on one membrane to improve image focus and resolution
  • Isolates/tethers biomolecules and nanomaterials through bifunctional linkers or immunocapture

 Applications:

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  • Environmental transformations of nanomaterials
  • Immobilization of biological structures on substrates
  • Dynamic imaging of self-assembly processes
  • On-grid assays

 Surface chemistry options include:

    • Silanization/chemical derivatization
    • Positive or negative surface charges
    • Custom hydrophobic/hydrophilic coatings
    • Self-assembled monolayers
    • Patterned surface chemistry
    • Immunospecific chemistries for purifying/isolating target analytes
STEM Image of 1.5 nm AuMES in water, immobilized on a Hummingbird fluid cell with a positively functionalized surface. (Image taken with a Hummingbird Scientific holder, courtesy of John Miller, Dune Sciences Inc.)
STEM Image of 1.5 nm Au MES in water, immobilized on a Hummingbird fluid cell with a positively-functionalized surface. (Image taken with a Hummingbird Scientific holder, courtesy of John Miller, Dune Sciences Inc.)

Contact Hummingbird Scientific directly for more information.

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